Antiproliferative and Proapoptotic Effects of Labisia pumila Ethanol Extract and Its Active Fraction in Human Melanoma HM3KO Cells

Figure 9

Representative Western blots showing the effect of SF2Lp at its IC₅₀ concentration (7.59 μg/mL) on the expression level of antiapoptotic Bcl-2 in HM3KO cells at different time intervals (3, 6, 12, and 24 hours). To confirm equal loading, the membrane was reprobed with β-actin. The data represent the mean ± SD of 3 independent experiments. *Significantly different at 𝑃<0.05 over control group.

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