Table 2: Results from ANOVA F-tests for the potency treatment (main effect and interaction with experimental day) in four different regions of interest (ROI).

Texture analysisMain effects (P value)Interaction with exp. day (P value)
parameterROI 0–50%ROI 50–70%ROI 70–90%ROI 90–100%ROI 0–50%ROI 50–70%ROI 70–90%ROI 90–100%

Cluster_prominence0.63440.3447<0.00010.06510.15570.01750.00850.0493
Cluster_shade0.00380.00020.15520.15840.67000.96040.83390.9768
Correlation0.64820.0938<0.00010.01310.0258<0.00010.01860.1024
Diagonal_moment0.0021<0.00010.14060.07640.46490.90910.83310.9135
Difference_energy0.67730.0160<0.00010.01310.02170.00010.03800.0419
Difference_entropy0.89240.0461<0.00010.01230.0186<0.00010.02400.0570
Energy0.72020.0170<0.00010.02350.02920.00010.03300.0467
Entropy0.93110.0578<0.00010.04160.0207<0.00010.01720.0351
Inertia0.65080.0939<0.00010.01450.0258<0.00010.01860.1158
Inverse_diff moment0.35310.0199<0.00010.00690.0103<0.00010.03790.0096
Kappa0.31370.0339<0.00010.00850.0120<0.00010.02710.0083
Maximum_probability0.46920.19790.01400.06530.18400.00910.37550.0246
Sum_energy0.12700.0550<0.00010.00080.0129<0.00010.06030.0498
Sum_entropy0.55500.1241<0.00010.00260.0280<0.00010.02890.0415
Sum_variance0.61930.0926<0.00010.00710.0260<0.00010.01800.0487

Note. Results from ANOVA F-tests for the potency treatment (Stannum met. 30x versus water 30x, main effect and interaction with experimental day), analysing all 15 second-order variables of texture analysis in four different regions-of-interest (ROI, defined as circular segments in % radius). Results originate from a full 3-way ANOVA with the independent experimental parameters (1) experimental day {LBI: 1–7, BRAD: 8–15; n = 15}, (2) treatment {Stannum met. 30x or water 30x; n = 2}, and (3) internal treatment replicate {1–3; n = 3}. Each experimental parameter combination (statistical treatment cell) was assessed by 6 biocrystallogram replicates. Highly significant effects (P < 0.01) are shown in bold.