Interaction between Red Yeast Rice and CYP450 Enzymes/P-Glycoprotein and Its Implication for the Clinical Pharmacokinetics of Lovastatin

<table>Plasma concentrations of lovastatin (a) and lovastatin acid (b) in healthy subjects after a single dose of one LipoCol Forte capsule alone or coadministration of gemfibrozil. The data are the mean ± SEM for 13 subjects.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 2

Figure 2: Interaction between Red Yeast Rice and CYP450 Enzymes/P-Glycoprotein and Its Implication for the Clinical Pharmacokinetics of Lovastatin 