Understanding the Molecular Mechanism of Interventions in Treating Rheumatoid Arthritis Patients with Corresponding Traditional Chinese Medicine Patterns Based on Bioinformatics Approach

Table 5

Pathways involved in the intersection between TCM cold and hot patterns in RA.

ID	Description	𝑃 value
51436	Negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle	3.14𝐸−78
31145	Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	3.14𝐸−78
51352	Negative regulation of ligase activity	8.96𝐸−78
51444	Positive regulation of ubiquitin-protein ligase activity	8.96𝐸−78
51437	Positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle	6.7𝐸−77
51443	Positive regulation of ubiquitin-protein ligase activity	1.76𝐸−76
51439	Regulation of ubiquitin-protein ligase activity during mitotic cell cycle	1.14𝐸−75
51351	Positive regulation of ligase activity	2.79𝐸−75
51438	Regulation of ubiquitin-prtein ligase activity	8.31𝐸−74
51340	Regulation of ligase activity	8.83𝐸−73