Beneficial Effect of Traditional Chinese Medicinal Formula Danggui-Shaoyao-San on Advanced Glycation End-Product-Mediated Renal Injury in Streptozotocin-Diabetic Rats

<table>(a) Renal immunostaining for NF-<i>κ</i>B, TGF-<i>β </i><sub>1</sub>, and type IV collagen expression in STZ-diabetic rats receiving 12 weeks of DSS (2.8 g kg<sup>−1</sup> per day) treatment. Original magnification, 200x. The vehicle (distilled water) used to disperse DSS was given at the same volume. (b) Semiquantitative assessments of the immunostaining for proteins were scored using 4 levels, and an average value was obtained from analyses of more than 30 glomeruli per rat. Values (mean ± SD) were obtained for each group of 4 animals. <sup>b</sup><svg height="11.375" id="M24" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared to the values of vehicle-treated STZ-diabetic rats, respectively.</table>

Evidence-Based Complementary and Alternative Medicine

fig2

Figure 2

Figure 2: Beneficial Effect of Traditional Chinese Medicinal Formula Danggui-Shaoyao-San on Advanced Glycation End-Product-Mediated Renal Injury in Streptozotocin-Diabetic Rats 

Figure 2 | Beneficial Effect of Traditional Chinese Medicinal Formula Danggui-Shaoyao-San on Advanced Glycation End-Product-Mediated Renal Injury in Streptozotocin-Diabetic Rats 