Beneficial Effect of Traditional Chinese Medicinal Formula Danggui-Shaoyao-San on Advanced Glycation End-Product-Mediated Renal Injury in Streptozotocin-Diabetic Rats

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td align="left">Groups</td><td align="center">Kidney weight (g)</td><td align="center">Kidney weight/body weight (mg g<sup>−1</sup>)</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td align="left">Nondiabetic rats</td><td align="center"></td><td align="center"></td></tr><tr><td align="left"> Vehicle</td><td align="center">1.5 ± 0.2<sup>d</sup></td><td align="center">5.6 ± 0.4<sup>d</sup></td></tr><tr><td align="left">STZ-diabetic rats</td><td align="center"></td><td align="center"></td></tr><tr><td align="left"> Vehicle</td><td align="center">2.9 ± 0.3<sup>b</sup></td><td align="center">16.5 ± 0.5<sup>b</sup></td></tr><tr><td align="left"> DSS (2.8 g kg<sup>−1</sup> per day)</td><td align="center">2.1 ± 0.3<sup>b</sup></td><td align="center">12.3 ± 0.2<sup>b, c</sup></td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td>Values (mean ± SD) were obtained for each group of 7 animals. <sup>b</sup><svg height="11.375" id="M18" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared to the values of vehicle-treated STZ-diabetic rats, respectively.<br/></td></tr></table>

Changes of the hypertrophy-related parameters in STZ-diabetic rats receiving 12 weeks of DSS treatment.

Evidence-Based Complementary and Alternative Medicine

tab3

Table 3

Table 3: Beneficial Effect of Traditional Chinese Medicinal Formula Danggui-Shaoyao-San on Advanced Glycation End-Product-Mediated Renal Injury in Streptozotocin-Diabetic Rats 

Table 3 | Beneficial Effect of Traditional Chinese Medicinal Formula Danggui-Shaoyao-San on Advanced Glycation End-Product-Mediated Renal Injury in Streptozotocin-Diabetic Rats 