Evidence for Inhibitory Effects of Flupirtine, a Centrally Acting Analgesic, on Delayed Rectifier K+ Currents in Motor Neuron-Like Cells
Figure 4
Effect of Flu on steady-state inactivation of in NSC-34 cells. (a) Superimposed current traces obtained in the absence (upper) and presence (lower) of 3 M Flu. The conditioning voltage pulses with a duration of 10 sec to various membrane potentials. The voltage protocol used is shown in the uppermost part. (b) Steady-state inactivation of obtained in the absence (■) and presence (□) of 3 M Flu (mean ± SEM; –11 for each point).