Ferulic Acid, an Angelica sinensis-Derived Polyphenol, Slows the Progression of Membranous Nephropathy in a Mouse Model

Table 1

Ferulic acid attenuates the severity of serum and urine parameters in MN mouse model.

		NC (𝑛=9)	N-T (𝑛=8)	Pre-T (𝑛=11)	Post-T (𝑛=12)
	Cr. (mg/dL)	0.51 ± 0.16	0.43 ± 0.06	0.47 ± 0.12	0.37 ± 0.08
Blood	T. chol. (mg/dL)	187.36 ± 24.7^*	447.58 ± 38.41	249.06 ± 72.33^*	226.37 ± 56.91^*
	Alb. (g/dL)	2.23 ± 0.17^*	1.64 ± 0.34	2.00 ± 0.19^*	2.08 ± 0.15^*
Urine	DPL (UP/UCr)	0.47 ± 0.08^*	1.28 ± 0.04	0.51 ± 0.21^*	0.49 ± 0.15^*

Data are expressed as mean ± SD.
^∗𝑃<0.05 versus N-T group.
NC: normal control, N-T: no treatment, Pre-T: treatment at induction of MN, Post-T: treatment after full-blown MN, BUN: blood urea nitrogen, Cr: creatinine, T.chol: total cholesterol, Alb: albumin, and DPL (U_p/U_cr): daily protein loss (urine protein/urine creatinine).