Research Article

Two Different Isomers of Vitamin E Prevent Bone Loss in Postmenopausal Osteoporosis Rat Model

Figure 5

Photomicrographs of distal femur metaphyses from ovariectomized (a) and sham-operated (b) rats, as well as ovariectomized rats treated with alpha-tocopherol (c) and tocotrienol (d). Undecalcified histological bone sections stained with Von Kossa. Trabecular bones appear dark by Von Kossa staining. Loss of trabecular bone is apparent in A while treatment with either forms of Vitamin E prevented bone loss in ovariectomized rats ((c) and (d)). Light microscopy at magnification ×40.
161527.fig.005a
(a) Ovariectomy control
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(b) Sham-operated
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(c) Ovariectomy + alpha-tocopherol
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(d) Ovariectomy + pure tocotrienol