Hepatoprotective Effects of Panus giganteus (Berk.) Corner against Thioacetamide- (TAA-) Induced Liver Injury in Rats

Table 3

Effects of different treatments on serum liver biomarkers of experimental rats.

Group	ALP (IU/L)	ALT (IU/L)	AST (IU/L)	GGT (IU/L)	Bilirubin (μmol/L)	Total protein (g/L)	Albumin (g/L)
Control (distilled water)	70.17 ± 5.62^a	46.50 ± 3.04^a	164.00 ± 14.68^a	5.00 ± 0.26^a	2.40 ± 0.20^a	69.33 ± 0.92^cd	13.50 ± 0.34^b
Control (P. giganteus)	79.17 ± 6.87^a	46.00 ± 1.59^a	151.00 ± 3.42^a	5.20 ± 0.40^a	2.60 ± 0.20^a	70.83 ± 0.79^d	13.83 ± 0.17^b
TAA control (200 mg/kg)	218.17 ± 5.47^c	65.33 ± 0.67^c	198.67 ± 0.21^b	12.67 ± 1.87^c	7.17 ± 0.83^c	63.83 ± 0.48^a	11.17 ± 0.40^a
Silymarin (50 mg/kg) + TAA	207.00 ± 11.93^c	56.33 ± 2.19^b	182.00 ± 5.82^ab	10.00 ± 0.52^bc	5.20 ± 0.31^b	65.50 ± 0.56^ab	12.83 ± 0.48^ab
Panus giganteus (0.5 g/kg) + TAA	165.67 ± 5.67^b	55.17 ± 2.34^b	174.00 ± 8.80^ab	7.17 ± 0.91^ab	5.00 ± 0.26^b	67.00 ± 0.26^bc	14.00 ± 0.68^b
Panus giganteus (1 g/kg) + TAA	166.67 ± 9.19^b	53.33 ± 0.80^ab	164.00 ± 4.37^a	6.83 ± 0.60^ab	4.80 ± 0.16^b	67.17 ± 0.60^bc	13.83 ± 0.40^b

Two month treatment; food and water ad libitum. All values are expressed as mean ± S.E.M.; 𝑛=6. Means with different letters (a–d) were significantly different at the level 𝑃<0.05. ALP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transferase.