Traditional Chinese Herbal Patch for Short-Term Management of Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial
Table 4
Changes in secondary outcomes.
Variable
Placebo ()
FNZG ()
SIG ()
WOMAC: Pain (range 0–20)
Day 7
Improvement from baseline
P value
0.988
0.310
Stiffness (range 0–8)
Day 7
Improvement from baseline
-0.78 (−1.10, −0.45)
P value
0.827
0.804
Physical function (range 0–68)
Day 7
Improvement from baseline
P value
0.564
0.820
Total score (score 0–96)
Day 7
Improvement from baseline
P value
0.800
0.616
Investigator TCMSQ subscaleSwelling (range 0–6)
Day 7
Improvement from baseline
P value
0.587
0.996
Range of motion (range 0–6)
Day 7
Improvement from baseline
P value
0.186
0.727
Fatigue in the region of waist and knee muscles (range 0–6)
Day 7
Improvement from baseline
P value
0.870
0.917
Fear of coldness (range 0–6)
Day 7
Improvement from baseline
P value
0.029
0.172
Values are the mean (95% confidence interval). P values were calculated by one-factor analysis of variance (ANOVA). WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index; TCMSQ: Traditional Chinese Medicine Syndrome Questionnaire.
