Neuroprotective Effect of Uncaria rhynchophylla in Kainic Acid-Induced Epileptic Seizures by Modulating Hippocampal Mossy Fiber Sprouting, Neuron Survival, Astrocyte Proliferation, and S100B Expression
Immunohistochemistry staining of Hematoxylin and Eosin (HE) and NeuN in hippocampal slices from PBS, KA-induced, and UR-pretreated groups. HE (blue) and NeuN (brown) positive staining in whole hippocampus (a), CA1 (b), CA3 (c), and Hilus regions in PBS group. HE (blue) and NeuN (brown) positive staining in whole hippocampus (e), CA1 (f), CA3 (g), and Hilus (h) regions in KA-induced group. HE (blue) and NeuN (brown) immunostaining in whole hippocampus (i), CA1 (j), CA3 (k), and Hilus (l) regions in UR-treated group. The left panel was captured at 40x magnification, while the others were at 400x magnification.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.