Neuroprotective Effect of Uncaria rhynchophylla in Kainic Acid-Induced Epileptic Seizures by Modulating Hippocampal Mossy Fiber Sprouting, Neuron Survival, Astrocyte Proliferation, and S100B Expression
Immunohistochemistry staining of HE and GABAA in hippocampal slices from PBS, KA-induced, and UR-treated groups. HE (blue) and S100B (brown) positive staining in whole hippocampus (a), CA1 (b), CA3 (c), and Hilus (d) regions in PBS group. HE (blue) and GABAA (brown) positive staining in whole hippocampus (e), CA1 (f), CA3 (g), and Hilus (h) regions in KA-Induced group. HE (blue) and GABAA (brown) positive staining in whole hippocampus (i), CA1 (j), CA3 (k), and Hilus (l) regions in UR-treated group. The left panel was captured at 40x magnification, while the others were at 400x magnification.
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