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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 197309, 14 pages
http://dx.doi.org/10.1155/2012/197309
Research Article

The Antitumor Activity of Antrodia camphorata in Melanoma Cells: Modulation of Wnt/β-Catenin Signaling Pathways

1Department of Cosmeceutics, College of Pharmacy, China Medical University, Taichung 40402, Taiwan
2Institute of Nutrition, China Medical University, Taichung 40402, Taiwan
3Department of Medical Research, Chi Mei Medical Center, Tainan 710, Taiwan
4Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung 80708, Taiwan
5Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung 80708, Taiwan

Received 6 July 2012; Accepted 14 August 2012

Academic Editor: Olumayokun A. Olajide

Copyright © 2012 You-Cheng Hseu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [14 citations]

The following is the list of published articles that have cited the current article.

  • Zhaolin Chen, Taotao Ma, Cheng Huang, Lei Zhang, Xiongwen Lv, Tao Xu, Tingting Hu, and Jun Li, “MiR-27a modulates the MDR1/P-glycoprotein expression by inhibiting FZD7/β-catenin pathway in hepatocellular carcinoma cells,” Cellular Signalling, 2013. View at Publisher · View at Google Scholar
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  • Kuo-Hsun Chiu, Che-Hsin Lee, Chen-Hsun Liu, Wen-Sheng Liu, Yu-Diao Kuan, Wei-Kuang Wang, and Fu-Hsin Chang, “The Extract of Rhodobacter sphaeroides Inhibits Melanogenesis through the MEK/ERK Signaling Pathway,” Marine Drugs, vol. 11, no. 6, pp. 1899–1908, 2013. View at Publisher · View at Google Scholar
  • Hsin-Ling Yan, K. J. Senthil Kumar, Ya-Ting Kuo, Hebron C. Chang, Jiunn-Wang Liao, Li-Sung Hsu, and You-Cheng Hseu, “Antrodia camphorata induces G(1) cell-cycle arrest in human premyelocytic leukemia (HL-60) cells and suppresses tumor growth in athymic nude mice,” Food & Function, vol. 5, no. 9, pp. 2278–2288, 2014. View at Publisher · View at Google Scholar
  • Cheng-Han Chung, Szu-Chien Yeh, Chun-Jen Chen, and Kung-Ta Lee, “ Coenzyme Q0 from Antrodia cinnamomea in Submerged Cultures Induces Reactive Oxygen Species-Mediated Apoptosis in A549 Human Lung Cancer Cells ,” Evidence-Based Complementary and Alternative Medicine, vol. 2014, pp. 1–10, 2014. View at Publisher · View at Google Scholar
  • M. Carmen Morán, Tatiana Tozar, Agota Simon, Andra Dinache, Adriana Smarandache, Ionut Relu Andrei, Mihai Boni, Mihail Lucian Pascu, Francesca Cirisano, and Michele Ferrari, “Toxicity study in blood and tumor cells of laser produced medicines for application in fabrics,” Colloids and Surfaces B: Biointerfaces, 2015. View at Publisher · View at Google Scholar
  • Chien-Hsin Chang, Tur-Fu Huang, Kung-Tin Lin, Chun-Chieh Hsu, Wei-Luen Chang, Shih-Wei Wang, Feng-Nien Ko, Hui-Chin Peng, and Ching-Hu Chung, “4-Acetylantroquinonol B Suppresses Tumor Growth and Metastasis of Hepatoma Cells via Blockade of Translation-Dependent Signaling Pathway and VEGF Production,” Journal of Agricultural and Food Chemistry, vol. 63, no. 1, pp. 208–215, 2015. View at Publisher · View at Google Scholar
  • Ningning Liu, Ning Zhou, Ni Chai, Xuan Liu, Haili Jiang, Qiong Wu, and Qi Li, “Helicobacter pylori promotes angiogenesis depending on Wnt/beta-catenin-mediated vascular endothelial growth factor via the cyclooxygenase-2 pathway in gastric cancer,” BMC Cancer, vol. 16, no. 1, 2016. View at Publisher · View at Google Scholar
  • Hui-Min Wang, Hsin-Ling Yang, Varadharajan Thiyagarajan, Tzu-Hsiang Huang, Pei-Jane Huang, Ssu-Ching Chen, Jer-Yuh Liu, Li-Sung Hsu, Hsueh-Wei Chang, and You-Cheng Hseu, “ Coenzyme Q 0 Enhances Ultraviolet B–Induced Apoptosis in Human Estrogen Receptor–Positive Breast (MCF-7) Cancer Cells ,” Integrative Cancer Therapies, vol. 16, no. 3, pp. 385–396, 2016. View at Publisher · View at Google Scholar
  • Ching-Wen Chang, Te-Chang Lee, Yu-Syuan Chen, Chin-Chu Chen, Shiu-Huey Chou, Chung-Ji Liu, Jeng-Fan Lo, Chien-Chih Chen, Ik-On Chan, Sen-Je Sheu, and Ting-wei Lin, “Targeting cancer initiating cells by promoting cell differentiation and restoring chemosensitivity via dual inactivation of STAT3 and src activity using an active component of antrodia cinnamomea mycelia,” Oncotarget, vol. 7, no. 45, pp. 73016–73031, 2016. View at Publisher · View at Google Scholar
  • You-Cheng Hseu, Yu-Hsien Chao, Kai-Yuan Lin, Tzong-Der Way, Hui-Yi Lin, Varadharajan Thiyagarajan, and Hsin-Ling Yang, “Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/β-catenin signaling pathways in human colon cancer cells,” Journal of Ethnopharmacology, 2017. View at Publisher · View at Google Scholar
  • Jyh-Jye Wang, Chih-Chung Wu, Chun-Lin Lee, Shu-Ling Hsieh, Jin-Bor Chen, and Chu-I Lee, “Antimelanogenic, Antioxidant and Antiproliferative Effects of Antrodia camphorata Fruiting Bodies on B16-F0 Melanoma Cells,” Plos One, vol. 12, no. 1, pp. e0170924, 2017. View at Publisher · View at Google Scholar
  • You-Cheng Hseu, Geng-Ruei Chang, Jian-You Pan, Peramaiyan Rajendran, Dony Chacko Mathew, Mei-Ling Li, Jiunn-Wang Liao, William Tzu-Liang Chen, and Hsin-Ling Yang, “ Antrodia camphorata inhibits epithelial-to-mesenchymal transition by targeting multiple pathways in triple-negative breast cancers ,” Journal of Cellular Physiology, 2018. View at Publisher · View at Google Scholar