Chinese Medicine Injection Qingkailing for Treatment of Acute Ischemia Stroke: A Systematic Review of Randomized Controlled Trials

Table 1

Characteristics and methodological quality of included studies.

Study ID	Sample	Time of onset	CT/MRI	Intervention in control group	QKL injection dose/day	Course	Followup (month)	Death	Adverse effect
Liang 2000 [15]	80	<72 h	Yes	Conventional treatment	30 mL	14 d	1	No	Unclear
Tan et al. 2003 [10]	65	<72 h	Yes	Conventional treatment	40 mL	14 d	No	2/2	2 eruption and 1 dizziness
Wu et al. 2007 [14]	88	<72 h	Yes	Conventional treatment	1200 mg (freeze-drying agent, roughly equivalent to 60 mL)	14 d	No	No	Unclear
Yan and Li 2010 [13]	150	<6 h	Yes	Urokinase + conventional treatment	40 mL	7 d	No	No	No
Yang et al. 2003 [12]	58	<72 h	Yes	Conventional treatment	80 mL	20 d	No	No	No
Zeng and Feng 2003 [11]	64	<24 h	Yes	Conventional treatment	60 mL	20 d	No	No	Unclear
Yu and Liao 1999 [16]	40	<72 h	Yes	Conventional treatment	50 mL	14 d	1	1/7	No

Conventional medicine treatment includes mannital, dextran, nimodipine, aspirin, and so on.