Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Fig 5

Research Article

Propolis Prevents Hepatorenal Injury Induced by Chronic Exposure to Carbon Tetrachloride

Figure 5

(a) Photomicrograph of control liver with polygonal hepatocytes cordially arranged around hepatic central vein. Hepatic nuclei (N), uniform sinusoidal spaces (S) terminating into central vein (CV) were clearly visible (200x). (b) Liver sections of CCl4 induced chronic hepatic injury with disturbed cord arrangement of hepatocytes, vacuolation (V) due to collapsed cellular membranes, high accumulation of nonparenchymal or inflammatory cells (NP) and irregular sinusoids (200x). (c and d) Liver sections of CCl4 induced chronic hepatic injury with disturbed cord arrangement of hepatocytes and high degree of vacuolation (V) due to collapsed cellular membranes (400x). (e) Photomicrograph of liver after propolis therapy with minimal degree of vacuolation, better formed polygonal hepatocytes cordially arranged towards hepatic central vein (CV). Hepatic nuclei (N), uniform sinusoids (S) terminating into central vein were clearly visible (200x). (f) Silymarin therapy with better formed features of liver histology as comparable to experimental control (400x).
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