Research Article

Protective Role of Phyllanthus niruri Extract against Thioacetamide-Induced Liver Cirrhosis in Rat Model

Table 1

Effects of 2 g/kg and 5 g/kg PN ethanol extract on liver biochemical parameters.

GroupsALT (IU/L)AST (IU/L) ALP (IU/L)Total protein (g/L)Albumin (g/L)Total bilirubin (μmol/L)G-glutamyl transferase (IU/L)

Tween 20 (10%) 4 5 . 0 0 ± 5 . 3 2 2 7 . 0 0 ± 4 . 1 6 9 7 . 6 7 ± 1 3 . 8 6 7 3 . 0 0 ± 2 . 9 6 4 4 . 1 7 ± 2 . 5 9 1 0 . 1 7 ± 2 . 2 6 5 8 . 1 7 ± 9 . 9 0
PN extract (2 g/kg) 4 9 . 6 7 ± 4 . 6 0 2 6 . 3 3 ± 3 . 2 2 9 2 . 6 7 ± 9 . 7 6 7 4 . 5 0 ± 2 . 3 1 4 2 . 8 3 ± 1 . 9 7 8 . 0 0 ± 1 . 0 6 3 7 . 6 7 ± 6 . 8 2
PN extract (5 g/kg) 4 5 . 1 7 ± 5 . 3 0 2 8 . 0 0 ± 3 . 6 5 7 8 . 3 3 ± 6 . 8 1 7 4 . 3 3 ± 2 . 7 2 4 2 . 5 0 ± 2 . 9 3 9 . 5 0 ± 1 . 6 9 5 5 . 0 0 ± 8 . 8 3

Values were expressed as mean ± S.E.M. There are no statistically significant differences between the measurements in different groups. The significant value was set at 𝑃 < 0 . 0 5 .