Research Article

Protective Role of Phyllanthus niruri Extract against Thioacetamide-Induced Liver Cirrhosis in Rat Model

Table 3

Body, liver, and spleen weights of the rats in different groups.

GroupsBody wt. (gm)Liver wt. (gm)Liver index (%)Spleen wt. (gm)Spleen index (%)

Control 2 3 7 . 0 ± 1 7 . 2 4 6 . 2 ± 0 . 4 9 2 . 6 3 ± 0 . 1 3 0 . 3 6 ± 0 . 0 2 0 . 1 6 ± 0 . 0 2
TAA 1 9 5 . 4 ± 1 8 . 3 5 9 . 4 ± 0 . 9 8 4 . 8 1 ± 0 . 2 3 a 0 . 5 1 ± 0 . 1 0 0 . 2 5 ± 0 . 0 4
Silymarin 2 2 2 . 0 ± 1 2 . 0 0 9 . 2 ± 0 . 9 7 4 . 1 0 ± 0 . 2 2 0 . 5 3 ± 0 . 0 4 0 . 2 4 ± 0 . 0 1
PN 100 mg/kg 2 5 8 . 6 ± 1 4 . 0 2 8 . 2 ± 1 . 0 2 3 . 2 2 ± 0 . 4 1 b 0 . 4 6 ± 0 . 0 4 0 . 1 8 ± 0 . 0 2
PN 200 mg/kg 2 5 3 . 4 ± 1 6 . 4 1 7 . 8 ± 0 . 5 8 3 . 1 8 ± 0 . 2 4 c 0 . 4 0 ± 0 . 0 4 0 . 1 6 ± 0 . 0 1

The data were stated as mean ± S.E.M. Means with different superscripts are significantly different. a 𝑃 < 0 . 0 5 versus normal control group, b 𝑃 < 0 . 0 5 versus TAA control group, and c 𝑃 < . 0 1 versus TAA control group.