Evidence-Based Complementary and Alternative Medicine

Research Article

Protective Role of Phyllanthus niruri Extract against Thioacetamide-Induced Liver Cirrhosis in Rat Model

Table 4

Effects of TAA, PN, and silymarin on antioxidant enzymes activities.
GroupsTAC (mM)CAT (nmol/min/mL)SOD (U/mL)MDA (μM)GPX (nmol/min/mL)
Control 7 . 8 3 ± 1 . 4 7 8 4 8 . 3 ± 2 . 1 1 2 4 6 . 6 ± 4 . 1 2 3 0 . 1 0 ± 9 . 0 9 1 4 3 8 . 4 ± 1 . 4
TAA 4 . 4 8 ± 1 . 5 4 9 6 4 . 9 ± 4 . 5 a 3 1 0 . 3 ± 1 0 . 0 a 5 9 . 7 7 ± 8 . 4 1 a 1 4 6 6 . 1 ± 2 . 0
Silymarin 8 . 3 7 ± 0 . 4 3 b 8 3 9 . 7 ± 4 8 . 3 c 2 8 0 . 2 ± 1 2 . 3 3 0 . 4 3 ± 2 . 5 3 c 1 4 3 7 . 8 ± 5 5 . 9
PN 100 mg/kg 6 . 7 3 ± 0 . 2 1 8 9 8 . 3 ± 1 . 9 2 9 3 . 6 ± 2 9 . 2 3 7 . 7 7 ± 8 . 3 5 b 1 4 5 7 . 0 ± 3 6 . 1
PN 200 mg/kg 6 . 7 2 ± 0 . 9 1 8 5 4 . 0 3 ± 1 5 . 9 c 2 8 7 . 8 ± 5 . 5 5 2 9 . 1 0 ± 8 . 2 5 c 1 4 5 1 . 2 ± 9 . 4
The data were stated as mean ± S.D. Means with different superscripts are significantly different. a 𝑃 < 0 . 0 5 versus normal control group, b 𝑃 < 0 . 0 5 versus TAA control group, and c 𝑃 < 0 . 0 1 versus TAA control group.