Research Article

Cordyceps militaris Grown on Germinated Soybean Induces G2/M Cell Cycle Arrest through Downregulation of Cyclin B1 and Cdc25c in Human Colon Cancer HT-29 Cells

Figure 3

GSC BuOH extract induced G2/M phase cell cycle arrest in HT-29 cells. Cell cycle progression was examined by flow cytometry. (a) 0 μg/mL, (b) 25 μg/mL, (c) 50 μg/mL, (d) 75 μg/mL, (e) 100 μg/mL, and (f) 250 μg/mL. One representative of 3 independent experiments is shown (48 h treatments). Histograms show the findings during sub-G1, G1/G0, S, and G2/M phases of HT-29 cells. One-way ANOVA followed by Dunnett’s t-test was used for comparisons of multiple group means (* or * versus control).
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