Research Article

Betulinic Acid Inhibits Growth of Cultured Vascular Smooth Muscle Cells In Vitro by Inducing Arrest and Apoptosis

Figure 3

BrdU cell proliferation of VSMCs following treatment with IC25, IC50, and IC75 of BA for 24 h, 48 h and 72 h as compared to untreated and rapamycin-treated cell. The results are the mean ± S.E.M. of three separate experiments. Each data are significantly different among group with * (Student’s-t test). Anti-proliferative effects of BA on VSMCs in BrdU proliferation assay. The results shown are mean ± S.D. of OD (570 nm) of control and different treatments for 24, 48, and 72 h.
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