Systematic Review of Chinese Herbal Medicines for Preventing in-Stent Coronary Restenosis after Percutaneous Coronary Intervention

Table 5

Risk ratios of Chinese herbal medicines administered to prevent MACE after PCI.

Chinese herbal medicine	Number of studies	Number of patients	Risk ratio (RR)	95% CI of RR
Acute myocardial infarction
Bu xin yin plus RWM versus RWM	1 [76]	44	0.24	0.01~4.69
Dan hong tong mai capsule plus RWM versus RWM	1 [91]	138	0.14	0.01~2.64
Dan shen plus RWM versus RWM	2 [44, 85]	168	0.14	0.02~1.11
Fu fang dan shen pill plus RWM versus RWM	2 [50, 57]	156	0.32	0.03~2.99
Ku lie zi injection plus RWM versus RWM	1 [78]	40	0.33	0.01~7.72
Shu xin yin plus RWM versus RWM	1 [75]	44	0.24	0.01~4.69
Tong xin luo plus RWM versus RWM	2 [79, 90]	268	0.25	0.03~2.22
Xiong shao capsule plus RWM versus RWM	2 [40, 80]	173	0.14	0.02~1.06
Yi xin capsule plus RWM versus RWM	1 [77]	94	0.65	0.06~6.88
Overall (CHMs plus RWM versus RWM)	13	1125	0.22	0.10~0.49
Xiong shao capsule plus RWM versus RWM plus placebo	2 [73]	426	0.59	0.08~4.41
Overall (CHMs plus RWM versus RWM plus placebo)	2	426	0.59	0.08~4.41
Revascularization
Shu xin yin plus RWM versus RWM	1 [75]	44	0.69	0.23~2.01
Bu xin yin plus RWM versus RWM	1 [76]	44	0.69	0.23~2.01
Yi xin capsule plus RWM versus RWM	1 [77]	94	0.43	0.02~10.26
Xiong shao capsule plus RWM versus RWM	1 [40]	108	0.62	0.30~1.30
Overall (CHMs plus RWM versus RWM)	4	290	0.64	0.38~1.08
Xiong shao capsule plus RWM versus RWM plus placebo	2 [67, 81]	426	0.48	0.30~0.78
Overall (CHMs plus RWM versus RWM plus placebo)	2	426	0.48	0.30~0.78
Repeat PCI
Dan hong tong mai capsule plus RWM versus RWM	1 [91]	138	0.39	0.08~1.94
Dan shen plus RWM versus RWM	1 [52]	80	1.0	0.21~4.66
Fu fang dan shen pill plus RWM versus RWM	2 [50, 57]	156	0.14	0.03~0.58
Ku lie zi injection plus RWM versus RWM	1 [78]	40	0.33	0.01~7.72
Lei gong teng plus RWM versus RWM	1 [43]	80	0.56	0.20~1.51
Liang xue shen ji formula plus RWM versus RWM	1 [46]	97	0.54	0.14~2.14
Si ni tang plus RWM versus RWM	1 [59]	80	0.56	0.20~1.51
Tong xin luo plus RWM versus RWM	1 [90]	136	0.16	0.04~0.68
Overall (CHMs plus RWM versus RWM)	9	807	0.37	0.23~0.59
CABG
Dan hong tong mai capsule plus RWM versus RWM	1 [91]	138	0.14	0.01~2.64
Dan shen plus RWM versus RWM	1 [52]	80	Not	estimable
Fu fang dan shen pill plus RWM versus RWM	2 [50, 57]	156	0.32	0.03~2.99
Liang xue sheng ji formula plus RWM versus RWM	1 [46]	97	0.30	0.01~7.22
Tong xin luo plus RWM versus RWM	1 [90]	136	0.19	0.01~3.86
Xiong shao capsule plus RWM versus RWM	1 [40]	108	1.04	0.07~16.2
Overall (CHMs plus RWM versus RWM)	7	715	0.29	0.09~0.96
Xiong shao capsule plus RWM versus RWM plus placebo	2 [67, 81]	426	0.20	0.02~1.68
Overall (CHMs plus RWM versus RWM plus placebo)	2	426	0.20	0.02~1.68

CABG = coronary artery bypass graft; CHM = Chinese herbal medicine; CI = confidence interval; PCI = percutaneous coronary intervention; RWM = routine Western medicine; MACE = major adverse cardiac event.