Oreocnide integrifolia Flavonoids Augment Reprogramming for Islet Neogenesis and β-Cell Regeneration in Pancreatectomized BALB/c Mice

Figure 1

Represents (a) HPLC fingerprint of flavonoid rich fraction with marker compounds, (b) HPTLC fingerprint of Flavonoidal fraction derivatized with NP-PEG reagent, (c) schematic representation of experimental paradigm, (d and e) plasma blood glucose levels and insulin titers of Px and Px + FRF groups. All values are expressed as mean + SEM of six animals (one-way ANOVA) where, ^•𝑃<0.05, ^■𝑃<0.01, ^♦𝑃<0.001: sham was compared to other experimental groups; ^𝛿𝑃<0.001: Px day 7 was compared Px day 7 + FRF; white numbered 3 circle 𝑃<0.001: Px day 14 was compared to Px day 14 + FRF; black numbered 3 circle𝑃<0.001: Px day 21 was compared to Px day 21 + FRF.