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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 269397, 6 pages
Research Article

Mathematical Distinction in Action Potential between Primo-Vessels and Smooth Muscle

Acupuncture, Moxibustion & Meridian Research Center, Division of Standard Research, Korea Institute of Oriental Medicine, Daejeon 305-811, Republic of Korea

Received 15 September 2011; Accepted 24 October 2011

Academic Editor: Gerhard Litscher

Copyright © 2012 Seong-Jin Cho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We studied the action potential of Primo-vessels in rats to determine the electrophysiological characteristics of these structures. We introduced a mathematical analysis method, a normalized Fourier transform that displays the sine and cosine components separately, to compare the action potentials of Primo-vessels with those for the smooth muscle. We found that Primo-vessels generated two types of action potential pulses that differed from those of smooth muscle: (1) Type I pulse had rapid depolarizing and repolarizing phases, and (2) Type II pulse had a rapid depolarizing phase and a gradually slowing repolarizing phase.