Research Article

Polysaccharides from the Medicinal Mushroom Cordyceps taii Show Antioxidant and Immunoenhancing Activities in a D-Galactose-Induced Aging Mouse Model

Table 1

Effect of APCT on the thymus and spleen indices in D-galactose-induced aging mice.

GroupSITI

Normal4.23 ± 0.712.41 ± 0.74
Model3.99 ± 0.222.07 ± 0.44
100 mg/kg·d4.28 ± 1.132.73 ± 1.01
200 mg/kg·d4.48 ± 0.71*2.74 ± 0.72*
400 mg/kg·d4.34 ± 0.34*2.50 ± 0.59*

SI and TI represent the spleen and thymus indices, respectively. The normal group was administered with normal saline s.c. and water orally. The model group was administered with D-galactose (120 mg/kg, s.c.) and water orally. The positive control group was administered with D-galactose (120 mg/kg, s.c.) and vitamin C (100 mg/kg) orally. The APCT group was administered with D-galactose (120 mg/kg, s.c.) and APCT (100, 200, and 400 mg/kg) orally. All drugs were administered for 45 d. The values shown are the mean ± SD of 10 mice. *P < 0.05 and **P < 0.01 versus the model group.