Yang-Dan-Tang, Identified from 15 Chinese Herbal Formulae, Inhibits Human Lung Cancer Cell Proliferation via Cell Cycle Arrest

<table>CHM Formula 14 led to A549 cells arrested in G0/G1 and G2 phase. Cell cycle analysis of A549 cells after treatment with Formula 14. (a) Representative data of cell cycle distribution profile under Formula 14 treatment. Treatment with Formula 14 led to significant cell cycle arrest in G1 and G2 phase. (b) Quantified result of cells at different phases from (a). (c) Representative data of ki67 analysis of A549 cells after a 72 hr treatment of Formula 14. (d) Fraction of cells in G0 and other phases. Formula 14 significantly increased the G0 cell population after 72 hr treatment. Student’s <svg height="10.3875" id="M6" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 5.9250002 10.3875" width="5.9250002" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: Yang-Dan-Tang, Identified from 15 Chinese Herbal Formulae, Inhibits Human Lung Cancer Cell Proliferation via Cell Cycle Arrest 