Mitochondria Superoxide Anion Production Contributes to Geranylgeraniol-Induced Death in Leishmania amazonensis
Figure 6
Mitochondria production in Leishmania amazonensis promastigotes treated with geranylgeraniol for 2 h. Mitochondria production was evaluated using the fluorescent probe MitoSOX. Asterisks indicate significant difference relative to the control group (untreated parasites) as identified by variance analysis (one-way) with post hoc Tukey testing (*). Results are expressed as mean fluorescence (in arbitrary units) ± SD of at least three independent experiments.