Research Article
Interleukin-10 Genotype Correlated to Deficiency Syndrome in Hepatitis B Cirrhosis
Table 4
Correlation between IL-10 genotypes and Child-Pugh classification or compensation and decompensation phase in HBC patients.
| | Gene/genotype | Child-Pugh classification | | Phase | | | Class A (%) () | Class B (%) () | Class C (%) () | Compensation () | Decompensation () |
| | IL-10-592 A/C | | | | | | | | | AA | 104 (43.7) | 35 (46.7) | 13 (46.4) | 0.839 | 83 (40.9) | 69 (50.0) | 0.072 | | AC | 108 (45.4) | 35 (46.7) | 13 (46.4) | 95 (46.8) | 61 (44.2) | | CC | 26 (10.9) | 5 (6.7) | 2 (7.1) | 25 (12.3) | 8 (5.8) | | IL-10-819C/T | | | | | | | | | TT | 114 (47.5) | 36 (48.0) | 12 (42.9) | 0.770 | 90 (44.3) | 72 (51.4) | 0.076 | | CT | 103 (42.9) | 32 (42.7) | 15 (53.6) | 89 (43.8) | 61 (43.6) | | CC | 23 (9.6) | 7 (9.3) | 1 (3.6) | 24 (11.8) | 7 (5.0) | | IL-10-1082A/G | | | | | | | | | AA | 212 (88.3) | 65 (86.7) | 22 (78.6) | 0.340* | 182 (89.7) | 177 (88.5) | 0.710* | | AG | 27 (11.3) | 10 (13.3) | 6 (21.4) | 20 (9.9) | 23 (11.5) | | GG | 1 (0.4) | 0 (0) | 0 (0) | 1 (0.5) | 0 (0) |
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*Between AA and AG + GG of IL-10-1082A/G.
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