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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 305454, 10 pages
http://dx.doi.org/10.1155/2012/305454
Research Article

The Protective Effect of Apamin on LPS/Fat-Induced Atherosclerotic Mice

1Department of Pathology, School of Medicine, Catholic University of Daegu, 3056-6 Daemyung 4-Dong, Nam-Gu, Daegu 705-718, Republic of Korea
2School of Biomedical Sciences, Charles Sturt University, Bathurst, NSW 2795, Australia
3Department of Agricultural Biology, National Academy of Agricultural Science, Suwon 441-100, Republic of Korea

Received 10 October 2011; Revised 30 January 2012; Accepted 5 February 2012

Academic Editor: Myeong Soo Lee

Copyright © 2012 Soo-Jung Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [14 citations]

The following is the list of published articles that have cited the current article.

  • Sang Mi Han, Kwang Gill Lee, and Sok Cheon Pak, “Effects of cosmetics containing purified honeybee (Apis mellifera L.) venom on acne vulgaris,” Journal of Integrative Medicine, vol. 11, no. 5, pp. 320–326, 2013. View at Publisher · View at Google Scholar
  • Sang Mi Han, Kwang Gill Lee, Kwan Kyu Park, and Sok Cheon Pak, “Skin sensitization study of bee venom (Apis mellifera L.) in Guinea pigs and rats,” Cutaneous and Ocular Toxicology, vol. 32, no. 1, pp. 27–30, 2013. View at Publisher · View at Google Scholar
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  • Woo-Ram Lee, Kyung-Hyun Kim, Hyun-Jin An, Jung-Yeon Kim, Sun-Jae Lee, Sang-Mi Han, Sok Cheon Pak, and Kwan-kyu Park, “Apamin inhibits hepatic fibrosis through suppression of transforming growth factor β1-induced hepatocyte epithelial-mesenchymal transition,” Biochemical and Biophysical Research Communications, 2014. View at Publisher · View at Google Scholar
  • Jun Feng, Antai Li, Jingyuan Deng, Yanhua Yang, Lili Dang, Yuanpeng Ye, Yuxin Li, and Weiping Zhang, “miR-21 attenuates lipopolysaccharide-induced lipid accumulation and inflammatory response: potential role in cerebrovascular disease,” Lipids in Health and Disease, vol. 13, 2014. View at Publisher · View at Google Scholar
  • Yuva Bellik, “Bee venom: Its potential use in alternative medicine,” Anti-Infective Agents, vol. 13, no. 1, pp. 3–16, 2015. View at Publisher · View at Google Scholar
  • Jung-Yeon Kim, Kyung-Hyun Kim, Woo-Ram Lee, Hyun-Jin An, Sun-Jae Lee, Sang-Mi Han, Kwang-Gill Lee, Yoon-Yub Park, Kee-Sik Kim, Young-Soo Lee, and Kwan-Kyu Park, “Apamin inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration through suppressions of activated Akt and Erk signaling pathway,” Vascular Pharmacology, 2015. View at Publisher · View at Google Scholar
  • Chiara Ricci, and Nicola Ferri, “Natural occurring PDGF receptor inhibitors with potential anti-atherosclerotic properties,” Vascular Pharmacology, 2015. View at Publisher · View at Google Scholar
  • Woo-Ram Lee, Sok Cheon Pak, and Kwan-Kyu Park, “The Protective Effect of Bee Venom on Fibrosis Causing Inflammatory Diseases,” Toxins, vol. 7, no. 11, pp. 4758–4772, 2015. View at Publisher · View at Google Scholar
  • Sok Cheon Pakpp. 287–306, 2017. View at Publisher · View at Google Scholar
  • Laura Cornara, Marco Biagi, Jianbo Xiao, and Bruno Burlando, “Therapeutic Properties of Bioactive Compounds from Different Honeybee Products,” Frontiers in Pharmacology, vol. 8, 2017. View at Publisher · View at Google Scholar
  • Woon-Hae Kim, Hyun-Jin An, Jung-Yeon Kim, Mi-Gyeong Gwon, Hyemin Gu, Sun-Jae Lee, Ji Y. Park, Kyung-Duck Park, Sang-Mi Han, Min-Kyung Kim, and Kwan-Kyu Park, “Apamin inhibits TNF-α- and IFN-γ-induced inflammatory cytokines and chemokines via suppressions of NF-κB signaling pathway and STAT in human keratinocytes,” Pharmacological Reports, 2017. View at Publisher · View at Google Scholar
  • Se-Yun Cheon, Kyung-Sook Chung, Seong-Soo Roh, Yun-Yeop Cha, and Hyo-Jin An, “Bee Venom Suppresses the Differentiation of Preadipocytes and High Fat Diet-Induced Obesity by Inhibiting Adipogenesis,” Toxins, vol. 10, no. 1, pp. 9, 2017. View at Publisher · View at Google Scholar
  • Shuai Zhang, Yi Liu, Yang Ye, Xue-Rui Wang, Li-Ting Lin, Ling-Yong Xiao, Ping Zhou, Guang-Xia Shi, and Cun-Zhi Liu, “Bee venom therapy: Potential mechanisms and therapeutic applications,” Toxicon, 2018. View at Publisher · View at Google Scholar