Research Article

MART-10, a New Generation of Vitamin D Analog, Is More Potent than 1α,25-Dihydroxyvitamin D3 in Inhibiting Cell Proliferation and Inducing Apoptosis in ER+ MCF-7 Breast Cancer Cells

Table 2

The distribution of different phases of MCF-7 cell cycle after 1α,25(OH)2D3 or MART-10 treatment determined by flow cytometry with Annexin V-FITC and PI staining.

PI negative,
Annexin V negative
PI negative,
Annexin V positive
PI positive,
Annexin V positive

Control76.22%1.59%7.19%
1α,25(OH)2D3 (10−6 M)65.79%1.19%10.04%
MART-10
(10−7 M)
57.87%1.76%13.66%