Inhibitory Effect of Ginsenoside Rg1 on Vascular Smooth Muscle Cell Proliferation Induced by PDGF-BB Is Involved in Nitric Oxide Formation

Figure 1

Effect of Rg1 on PDGF-BB-induced VSMC proliferation (MTT assay, 𝑥±𝑠, 𝑛=7). The VSMCs were cultured for 24 h. Normal: vehicle; N+Rg1: Rg1 180 mg·L⁻¹; model: PDGF-BB 25 μg·L⁻¹; Rg1-L: Rg1 20 mg·L⁻¹ + PDGF-BB 25 μg·L⁻¹; Rg1-M: Rg1 60 mg·L⁻¹ +PDGF-BB 25 μg·L⁻¹; Rg1-H: Rg1 180 mg·L⁻¹ + PDGF-BB 25 μg·L⁻¹. Data were mean ± S.E.M. ^##Significant difference from normal control at 𝑃<0.01* significant difference from model control at 𝑃<0.05, and ** significant difference from model control at 𝑃<0.01.