Inhibitory Effect of Ginsenoside Rg1 on Vascular Smooth Muscle Cell Proliferation Induced by PDGF-BB Is Involved in Nitric Oxide Formation
Figure 5
Effect of Rg1 on the intracellular free concentration ([Ca2+]i) of VSMCs. The [Ca2+]i was detected after 3 minutes of PDGF-BB addition with Fura-2/AM loaded VSMCs, and Rg1 administrations were performed before 30 minutes of the addition of PDGF-BB. Normal : vehicle; model : PDGF-BB 25 μg·L−1; Rg1-L : Rg1 20 mg·L−1 + PDGF-BB 25 μg·L−1; Rg1-M : Rg1 60 mg·L−1 +PDGF-BB 25 μg·L−1; Rg1-H : Rg1 180 mg·L−1 + PDGF-BB 25 μg·L−1. Data were mean ± S.E.M. #Significant difference from normal control at ; *significant difference from model control at , **Significant difference from model control at .
