Adverse Drug Reactions in a Complementary Medicine Hospital: A Prospective, Intensified Surveillance Study
Table 5
Adverse drug reactions (ADRs) caused by complementary and alternative medicine (CAM) drugs.
Indication
Patients age, sex
Drug ingredient and route of application
Concomitant medication also possibly related* and route of application
ADR
Type of ADR
Causality
Rheumatoid arthritis
62, f
Equisetum/Formica s.c.
Arnica/levisticum s.c.
Local skin reaction (erythema)
B
Probable
Rheumatoid arthritis
62, f
Mistletoe plant extracta1 s.c.
—
Local skin reaction (erythema) (8 × 8 cm)
A
Probable
Mesothelioma cancer
65, m
Mistletoe plant extracta2 s.c.
—
Temp. >38.6°C; Local skin reaction (erythema) 15 × 10 cm
A
Probable
Breast cancer
41, f
Mistletoe plant extracta3 s.c.
Pamidronate, i.v
Temp. 39.6°C
A
Possible
Chronic hepatitis C
35, f
Fragaria vesca/Vitis vinifera p.o.
Maculopapular exanthema forearms
B
Possible
Depression
53, f
Gentiana, Bryophyllum p.o.
Metamizole p.o.
Drug eruption
B
Possible
*Drugs for which the causal relationship to the same ADR was also considered to be possible; a1Iscucin salicis A; a2Abnoba viscum fraxini 20 mg; a3Helixor M 1 mg. s.c.: subcutaneous, p.o.: per os, i.v. and intravenous.
