Anti-Hepatitis B Virus Effect and Possible Mechanism of Action of 3,4-O-Dicaffeoylquinic Acid In Vitro and In Vivo
Figure 3
Immunohistochemical staining of HBsAg in the liver of HBV transgenic mice (×40). (a) A control untreated HBV transgenic mouse showing the positive expression of HBsAg (brown stain); (b) a lamivudine (100 mg/kg) treated HBV transgenic mouse; (c) a 3,4-dicaffeoylquinic acid (100 mg/kg) treated HBV transgenic mouse; (d) a 3,4-dicaffeoylquinic acid (50 mg/kg) treated HBV transgenic mouse. (b), (c), and (d) show clear inhibition of HBsAg expression.
