Anti-Hepatitis B Virus Effect and Possible Mechanism of Action of 3,4-O-Dicaffeoylquinic Acid In Vitro and In Vivo

Table 1

Cytotoxicity of 3,4-dicaffeoylquinic acid in HL-7702 hepatocytes.

Groups	Concentration (μg/mL)	Absorbency (570 nm)	Cell survival (%)
Vehicle	—	1.275±0.042	100
Silybin	100	1.235±0.069	96.86
	50	1.238±0.038	97.10
	10	1.259±0.048	98.74
3,4-Dicaffeoylquinic acid	100	1.230±0.048	96.47
	50	1.246±0.027	97.72
	10	1.255±0.046	98.43

All determinations were performed in six replicates, and values were expressed as mean ± SD. No significant difference compared with the vehicle control.