Inhibitory Effects of Daiokanzoto (Da-Huang-Gan-Cao-Tang) on P-Glycoprotein
Figure 1
Inhibitory effects of Daiokanzoto on ATPase activity in the presence of various P-gp substrates. Daiokanzoto was added to a final concentration of 0.5 mg/mL (open column) or 1.0 mg/mL (closed column) together with verapamil, digoxin, vinblastine, or ketoconazole as the P-gp substrate (50 M). Data represent the mean SD of three experiments.