Luteolin Suppresses Inflammatory Mediator Expression by Blocking the Akt/NFκB Pathway in Acute Lung Injury Induced by Lipopolysaccharide in Mice
Figure 1
Effect of luteolin on LPS-induced histopathologic alterations in lung (400X). Histopathologic study of the lungs was performed at the end of 6 h right after LPS instillation. The lungs were removed immediately after the mice were sacrificed by thoracotomy, fixed in paraformaldehyde, embedded in paraffin, sectioned at 3 μm, and stained with H&E before observation. (a) Vehicle-treated/LPS (−) group; (b) vehicle-treated/LPS (+) group; (c) 70, (d) 35, and (e) 18 μmol/kg luteolin-treated/LPS (+) group.
