Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Fig 2

Research Article

Luteolin Suppresses Inflammatory Mediator Expression by Blocking the Akt/NFκB Pathway in Acute Lung Injury Induced by Lipopolysaccharide in Mice

Figure 2

Effect of luteolin on LPS-induced PMNs and protein accumulation in BALF. (a) PBS or 18–70 μmol/kg of luteolin were intraperitoneally injected for 30 min prior to intratracheal instillation of LPS (100 μg/50 μL saline) or saline in mice. Six hours later, the mice were anesthetized and BALF was collected for PMNs count. (b) Pulmonary permeability was determined by quantitating the protein content in cell-free BALF. (c) Pulmonary edema was determined by quantitating the wet/dry weight ratio. Values are expressed as means ± S.D. ( in each group). * versus control; # versus LPS group.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.