Effects of Buyang Huanwu Decoction on Ventricular Remodeling and Differential Protein Profile in a Rat Model of Myocardial Infarction

Table 1

MALDI-TOF MS identification of protein molecules with altered expression.

Spot no.^a	Accession no.	Protein score (threshold)^b	Molecular weight^c	Calculated pI value^c	Protein name	Expression level^d
1	P17209; MYL4_RAT	161 (23)	21282.18	4.96	Myosin light chain 4	↓, ⇓
2	Q08733; MLRV_RAT	174 (34)	18880.35	4.86	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform	↓, ⇓
3	01161 ANF_RAT	132 (34)	16555.55	6.73	Atrial natriuretic factor	↓, ⇓
4	P97541 HSPB6_RAT	82 (24)	17504.93	6.05	Heat shock protein beta-6	↑, ⇑
5	Q03336; RGN_RAT	75 (23)	33389.85	5.27	Regucalcin	↑, ⇑
6	O35244; PRDX6_RAT	66 (23)	24818.6	5.64	Peroxiredoxin-6	↑, ⇑
7	Q561S0; NDUAA_RAT	80 (23)	40493.09	7.64	NADH dehydrogenase	↑, ⇑
8	Q63347 PRS7_RAT	46 (27)	48574.78	5.59	26S protease regulatory subunit	↑
9	P61983 (1433G_RAT)	64 (27)	28302.59	4.80	14-3-3 protein gamma	↓
10	P02091 (HBB1_RAT)	73 (23)	15979.39	7.87	Hemoglobin subunit beta-1	↑
11	O35796 (C1QBP_RAT)	43 (23)	30996.92	4.77	Complement component 1 Q subcomponent-binding protein, mitochondrial	↓
12	P11884 (ALDH2_RAT)	49 (23)	56488.42	6.63	Aldehyde dehydrogenase, mitochondrial	↓

Notes: ^aDefined according to spot positions in 2-D gel indicated as in Figure 2.
^bProtein scores are derived from ions scores as a nonprobabilistic basis for ranking protein hits. Protein scores greater than threshold value are significant (𝑃<0.05).
^cMolecular weight value calculated by amino acid count; pI value calculated from the database entry without any processing.
^d ↑↓Expression of sham group compared to that of model group; ⇑⇓ expression of BDHWD group compared to that of model group.