Gastroprotective Activity of Polygonum chinense Aqueous Leaf Extract on Ethanol-Induced Hemorrhagic Mucosal Lesions in Rats

Table 1

The ulcer area, percentage of inhibition, gastric wall mucus (mg Alcian blue/g tissue), MDA (𝜇mol/g protein), SOD (U/g protein), and protein concentration (mg/mL tissue) of the groups.

Groups	Ulcer area	Inhibition %	GWM	MDA	Protein	SOD
1	—	—	245.13 ± 2.2*	70 ± 2.93*	10 ± 0.16*	236.13 ± 4.29*
2	921.90 ± 16.68	—	125.10 ± 2.3	228 ± 4.53	5.17 ± 0.12	121.15 ± 2.50
3	159.30 ± 5.04*	82.72	320.11 ± 2.4*	95.08 ± 3.3*	8.45 ± 0.16*	423.00 ± 5.83*
4	455 ± 12.16*	50.64	282.00 ± 1.8*	110 ± 4.23*	7.22 ± 0.06*	285.00 ± 4.83*
5	315.23 ± 9.17*	65.81	303.1 ± 2.5*	108 ± 3.65*	7.86 ± 0.04*	350.10 ± 4.29*
6	235.61 ± 7.39*	74.44	315.08 ± 2*	102.1 ± 3.7*	9.40 ± 0.12*	402.42 ± 5.95*
7	114.00 ± 5.41*	87.63	325.11 ± 4.4*	92.15 ± 3.2*	9.70 ± 0.14*	415.13 ± 6.90*

Values are assumed as mean ± S.E.M. The statistical analysis was assessed with one-way ANOVA (post hoc analysis) with 𝑃<0.05. *Significant differences when compared to group 2. (1) The normal control group. (2) the ulcer control group. (3) the reference control. (4) 62.50 mg/kg of the plant extract; (5) 125 mg/kg of the plant extract. (6) 250 mg/kg of the plant extract. (7) 500 mg/kg of the plant extract.