Efficacy of Bidens pilosa Extract against Herpes Simplex Virus Infection In Vitro and In Vivo
Effects of B. pilosa extract on mice cutaneously infected with HSV-1. Six mice in each group were infected. Extract (1 g/kg per dose) and ACV (5 mg/kg per dose) were orally applied twice daily before or after infection. Mice were monitored everyday for development of skin lesions (a) and survival (b). ◆, control (water treatment); □, B. pilosa extract pretreatment; , B. pilosa treatment; ×, ACV treatment.