Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Tab 1

Research Article

Randomised, Double Blind, Placebo-Controlled Trial of Echinacea Supplementation in Air Travellers

Table 1

Alkylamide content per Echinacea tablet used as trial medication.

Alkylamide nameMWStructuremg/tableta

(2E/Z,4Z/E)-N-(2-Methylpropyl)undeca-2,4-diene-8,10-diynamide229Diene0.247
(2E,4Z)-N-(2-Methylpropyl)dodeca-2,4-diene-8,10-diynamide243Diene0.505
(2E,4E,8Z/E,10Z/E)-N-(2-Methylpropyl)dodeca-2,4,8,10-tetraenamide247Diene1.504
(2E,4E,8Z)-N-(2-Methylpropyl)dodeca-2,4,8-trienamide249Diene0.078
(2E,4E)-N-(2-Methylpropyl)dodeca-2,4-dienamide251Diene0.166
(2E,4Z)-N-(2-Methylbutyl)dodeca-2,4-diene-8,10-diynamide257Diene0.130
(2E/Z)-N-(2-Methylpropyl)undec-2-ene-8,10-diynamide231Monoene0.699
(2E)-N-(2-Methylpropyl)dodec-2-ene-8,10-diynamide245Monoene0.452
(2E,7Z)-N-(2-Methylpropyl)trideca-2,7-diene-10,12-diynamide257Monoene0.081
(2E0-N-(2-Methylbutyl)dodec-2-ene-8,10-diynamide259Monoene0.186
(2E,9Z)-N-(2-Methylpropyl)pentadeca-2,9-diene-12,14-diynamide285Monoene0.330
(2E,9Z)-N-(2-Methylpropyl)hexadeca-2,9-diene-12,14-diynamide299Monoene0.041

Total4.419

a Alkylamide concentrations were determined by liquid chromatography mass spectrometry using a Shimadzu HPLC system coupled to a Shimadzu 2010EV single quadrupole mass spectrometer operating with an APCI interface as described for a previous batch [25].