Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 418953, 7 pages
http://dx.doi.org/10.1155/2012/418953
Research Article

Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging

1Institute of Natural Medicine, University of Toyama, Toyama 930-0194, Japan
2Graduate School of Biomedical Science, Nagasaki University, Nagasaki 852-8521, Japan
3Department of Food Science, Gyeongnam National University of Science and Technology, Gyeongnam 660-758, Republic of Korea
4Department of Oriental Medicine Resources and Research Institute of Korean Oriental Medicines, Sunchon National University, Jeonnam 540-742, Republic of Korea

Received 28 October 2011; Revised 3 February 2012; Accepted 11 February 2012

Academic Editor: Bhushan Patwardhan

Copyright © 2012 Chan Hum Park et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. Ahmed, “Advanced glycation endproducts—role in pathology of diabetic complications,” Diabetes Research and Clinical Practice, vol. 67, no. 1, pp. 3–21, 2005. View at Publisher · View at Google Scholar · View at Scopus
  2. P. Ulrich and A. Cerami, “Protein glycation, diabetes, and aging,” Recent Progress in Hormone Research, vol. 56, no. 1, pp. 1–21, 2001. View at Publisher · View at Google Scholar · View at Scopus
  3. J. Peyroux and M. Sternberg, “Advanced glycation endproducts (AGEs): pharmacological inhibition indiabetes,” Pathologie Biologie, vol. 54, no. 7, pp. 405–419, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. B. I. Freedman, J. P. Wuerth, K. Cartwright et al., “Design and baseline characteristics for the aminoguanidine clinical trial in overt type 2 diabetic nephropathy (ACTION II),” Controlled Clinical Trials, vol. 20, no. 5, pp. 493–510, 1999. View at Publisher · View at Google Scholar · View at Scopus
  5. T. Yokozawa, T. Nakagawa, and K. Terasawa, “Effects of Oriental medicines on the production of advanced glycation endproducts,” Journal of Traditional Medicines, vol. 18, no. 3, pp. 107–112, 2001. View at Google Scholar
  6. T. Hatano, R. Edamatsu, M. Hiramatsu et al., “Effects of the interaction of tannins with co-existing substances. VI. Effects of tannins and related polyphenols on superoxide anion radical, and on 1,1-diphenyl-2-picrylhydrazyl radical,” Chemical and Pharmaceutical Bulletin, vol. 37, no. 8, pp. 2016–2021, 1989. View at Google Scholar
  7. T. Yokozawa, C. P. Chen, E. Dong, T. Tanaka, G. I. Nonaka, and I. Nishioka, “Study on the inhibitory effect of tannins and flavonoids against the 1,1-diphenyl-2-picrylhydrazyl radical,” Biochemical Pharmacology, vol. 56, no. 2, pp. 213–222, 1998. View at Publisher · View at Google Scholar · View at Scopus
  8. T. Yokozawa, N. Yamabe, E. J. Cho, T. Nakagawa, and S. Oowada, “A study on the effects to diabetic nephropathy of Hachimi-jio-gan in rats,” Nephron - Experimental Nephrology, vol. 97, no. 2, pp. e38–e48, 2004. View at Publisher · View at Google Scholar · View at Scopus
  9. N. Yamabe, K. S. Kang, Y. Matsuo, T. Tanaka, and T. Yokozawa, “Identification of antidiabetic effect of iridoid glycosides and low molecular weight polyphenol fractions of Corni Fructus, a constituent of Hachimi-jio-gan, in streptozotocin-induced diabetic rats,” Biological and Pharmaceutical Bulletin, vol. 30, no. 7, pp. 1289–1296, 2007. View at Publisher · View at Google Scholar · View at Scopus
  10. N. Yamabe, K. S. Kang, E. Goto, T. Tanaka, and T. Yokozawa, “Beneficial effect of Corni Fructus, a constituent of Hachimi-jio-gan, on advanced glycation end-product-mediated renal injury in streptozotocin-treated diabetic rats,” Biological and Pharmaceutical Bulletin, vol. 30, no. 3, pp. 520–526, 2007. View at Publisher · View at Google Scholar · View at Scopus
  11. T. Yokozawa, N. Yamabe, H. Y. Kim et al., “Protective effects of morroniside isolated from Corni Fructus against renal damage in streptozotocin-induced diabetic rats,” Biological and Pharmaceutical Bulletin, vol. 31, no. 7, pp. 1422–1428, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. N. Yamabe, J. S. Noh, C. H. Park et al., “Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice,” European Journal of Pharmacology, vol. 648, no. 1–3, pp. 179–187, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. Y. W. Zhang, Y. W. Chen, and S. P. Zhao, “A sedoheptulose gallate from the fruits of Cornus officinalis,” Acta Pharmaceutica Sinica, vol. 34, no. 1, pp. 153–155, 1999. View at Google Scholar · View at Scopus
  14. T. Hatano, N. Ogawa, R. Kira, T. Yasuhara, and T. Okuda, “Tannins of cornaceous plants. I. Cornusiins A, B and C, dimeric monomeric and trimeric hydrolyzable tannins from Cornus officinalis, and orientation of valoneoyl group in related tannins,” Chemical and Pharmaceutical Bulletin, vol. 37, no. 8, pp. 2083–2090, 1989. View at Google Scholar · View at Scopus
  15. T. Hatano, T. Yasuhara, R. Abe, and T. Okuda, “A galloylated monoterpene glucoside and a dimeric hydrolysable tannin from Cornus officinalis,” Phytochemistry, vol. 29, no. 9, pp. 2975–2978, 1990. View at Google Scholar · View at Scopus
  16. T. Yokozawa, C. H. Park, J. S. Noh, T. Tanaka, and E. J. Cho, “Novel action of 7-O-galloyl-d-sedoheptulose isolated from Corni Fructus as a hypertriglyceridaemic agent,” Journal of Pharmacy and Pharmacology, vol. 61, no. 5, pp. 653–661, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. N. Yamabe, K. S. Kang, C. H. Park, T. Tanaka, and T. Yokozawa, “7-O-Galloyl-d-sedoheptulose is a novel therapeutic agent against oxidative stress and advanced glycation endproducts in the diabetic kidney,” Biological and Pharmaceutical Bulletin, vol. 32, no. 4, pp. 657–664, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. C. H. Park, J. S. Noh, N. Yamabe, K. S. Kang, T. Tanaka, and T. Yokozawa, “Beneficial effect of 7-O-galloyl-d-sedoheptulose on oxidative stress and hepatic and renal changes in type 2 diabetic db/db mice,” European Journal of Pharmacology, vol. 640, no. 1–3, pp. 233–242, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. C. H. Park, J. S. Noh, T. Tanaka, K. Uebaba, E. J. Cho, and T. Yokozawa, “The effects of Corni Fructus extract and its fractions against α-glucosidase inhibitory activities in vitro and sucrose tolerance in normal rats,” The American Journal of Chinese Medicine, vol. 39, no. 2, pp. 367–380, 2011. View at Publisher · View at Google Scholar
  20. G. Münch, M. Gerlach, J. Sian, A. Wong, and P. Riederer, “Advanced glycation end products in neurodegeneration: more than early markers of oxidative stress?” Annals of Neurology, vol. 44, no. 3, pp. S85–S88, 1998. View at Google Scholar · View at Scopus
  21. P. Gillery, “Advanced glycation end products (AGEs), free radicals and diabetes,” Journal de la Société de biologie, vol. 195, no. 4, pp. 387–390, 2001. View at Google Scholar · View at Scopus
  22. T. Tanaka, R. Takahashi, I. Kouno, and G. I. Nonaka, “Chemical evidence for the de-astringency (insolubilization of tannins) of persimmon fruit,” Journal of the Chemical Society, Perkin Transactions, no. 20, pp. 3013–3022, 1994. View at Google Scholar · View at Scopus
  23. J. A. Vinson and T. B. Howard, “Inhibition of protein glycation and advanced glycation end products by ascorbic acid and other vitamins and nutrients,” The Journal of Nutritional Biochemistry, vol. 7, no. 12, pp. 659–663, 1996. View at Publisher · View at Google Scholar · View at Scopus
  24. N. Mateus, E. Carvalho, C. Luís, and V. de Freitas, “Influence of the tannin structure on the disruption effect of carbohydrates on protein-tannin aggregates,” Analytica Chimica Acta, vol. 513, no. 1, pp. 135–140, 2004. View at Publisher · View at Google Scholar · View at Scopus
  25. G. K. B. Lopes, H. M. Schulman, and M. Hermes-Lima, “Polyphenol tannic acid inhibits hydroxyl radical formation from Fenton reaction by complexing ferrous ions,” Biochimica et Biophysica Acta, vol. 1472, no. 1-2, pp. 142–152, 1999. View at Publisher · View at Google Scholar · View at Scopus
  26. W. M. Cort, J. W. Scott, M. Araujo et al., “Antioxidant activity and stability of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid,” Journal of the American Oil Chemists' Society, vol. 52, no. 6, pp. 174–178, 1975. View at Publisher · View at Google Scholar · View at Scopus
  27. P. J. Thornalley, A. Yurek-George, and O. K. Argirov, “Kinetics and mechanism of the reaction of aminoguanidine with the α-oxoaldehydes glyoxal, methylglyoxal, and 3-deoxyglucosone under physiological conditions,” Biochemical Pharmacology, vol. 60, no. 1, pp. 55–65, 2000. View at Publisher · View at Google Scholar · View at Scopus
  28. D. L. Price, P. M. Rhett, S. R. Thorpe, and J. W. Baynes, “Chelating activity of advanced glycation end-product inhibitors,” The Journal of Biological Chemistry, vol. 276, no. 52, pp. 48967–48972, 2001. View at Publisher · View at Google Scholar · View at Scopus
  29. I. Giardino, A. K. Fard, D. L. Hatchell, and M. Brownlee, “Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis,” Diabetes, vol. 47, no. 7, pp. 1114–1120, 1998. View at Publisher · View at Google Scholar · View at Scopus