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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 428560, 10 pages
Research Article

Herb-Drug Interaction of Paullinia cupana (Guarana) Seed Extract on the Pharmacokinetics of Amiodarone in Rats

1Laboratory of Pharmacology, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, Portugal
2Centre for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-517 Coimbra, Portugal
3Health Sciences Research Centre (CICS), University of Beira Interior (UBI), 6200-506 Covilhã, Portugal
4Department of Internal Medicine, Amato Lusitano Hospital, 6000-085 Castelo Branco, Portugal

Received 14 September 2012; Accepted 10 November 2012

Academic Editor: Ken Yasukawa

Copyright © 2012 Márcio Rodrigues et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • Márcio Rodrigues, Gilberto Alves, and Amílcar Falcão, “Investigating herb–drug interactions: the effect of Citrus aurantium fruit extract on the pharmacokinetics of amiodarone in rats,” Food and Chemical Toxicology, 2013. View at Publisher · View at Google Scholar
  • K. Ghedira, and P. Goetz, “Guarana, Paullinia cupana Kunth ex H.B.K. var. sorbilis (Sapindaceae),” Phytothérapie, vol. 11, no. 2, pp. 121–125, 2013. View at Publisher · View at Google Scholar
  • A. L. Souza, P. C. S. Angelo, P. P. O. Nogueira, J. F. C. Goncalves, A. M. Franco, S. Astolfi-Filho, J. L. Lopez-Lozano, and E. V. Andrade, “Method for obtaining high-resolution proteomic analysis from pericarps of guarana,” Genetics and Molecular Research, vol. 13, no. 3, pp. 8014–8024, 2014. View at Publisher · View at Google Scholar
  • Dimitrios Moustakas, Michael Mezzio, Branden R. Rodriguez, Mic Andre Constable, Margaret E. Mulligan, and Evelyn B. Voura, “Guarana Provides Additional Stimulation over Caffeine Alone in the Planarian Model,” Plos One, vol. 10, no. 4, 2015. View at Publisher · View at Google Scholar
  • Andre L. D. A. Mazzari, Flora Milton, Samantha Frangos, Ana C. B. Carvalho, Dâmaris Silveira, Francisco de Assis Rocha Neves, and Jose M. Prieto, “In vitro Effects of Four Native Brazilian Medicinal Plants in CYP3A4 mRNA Gene Expression, Glutathione Levels, and P-Glycoprotein Activity,” Frontiers in Pharmacology, vol. 7, 2016. View at Publisher · View at Google Scholar
  • Cláudia G. Latorre Palma, Auro Del Giglio, Andrea Thaumaturgo Lera, Tatiana Lerner, Manuella Missawa De Oliveira, Thaís Mazará De Borta, Renata Possebon Barbosa, Gisele Mendes Brito, Camila Ada Guazzelli, and Felipe José Melo Cruz, “Guarana (Paullinia cupana) Improves Anorexia in Patients with Advanced Cancer,” Journal of Dietary Supplements, vol. 13, no. 2, pp. 221–231, 2016. View at Publisher · View at Google Scholar