Evaluation of Hepatoprotective Effect of Leaves of Cassia sophera Linn.

Table 1

Effect of EECS and silymarin on serum biochemical parameters.

Biochemical parameters	Control	CCl4 1 mL/kg	MECS (200 mg/kg) + CCl4	MECS (400 mg/kg) + CCl4	Silymarin (50 mg/kg) + CCl4
ALT (IU/L)	84±5.4	178.3±10.1^a	151.6±11.1^∗	135.3±3.4^∗	120.0±3.9^∗
AST (IU/L)	143.3±14.8	251.6±11.9^a	220.0±11.5^∗	180.8±13.1^∗	158.3±10.6^∗
ALP (IU/L)	82.2±7.8	190.0±13.9^a	173.3±13.1^∗	130.5±9.5^∗	108±5.2^∗
Total protein (mg/dL)	6.9±0.32	3.5±0.46^a	4.6±0.28	5.2±0.21^∗∗	6.0±0.31
Total bilirubin (mg/dL)	0.29±0.04	0.98±0.07^a	0.79±0.07	0.63±0.05^∗∗	0.48±0.07^∗

Values are mean ±SEM (𝑛=6). * 𝑃<0.01 (moderately significant), ** 𝑃<0.05 (significant) as compared with CCl₄, ^a: significant as compared with control (𝑃<0.01).