Role of Mesotherapy in Musculoskeletal Pain: Opinions from the Italian Society of Mesotherapy

Table 1

Tissue levels of Na-ketoprofen (μg) detected by chromatography following local intradermal (LIT) or intramuscular (IM) administration, modified with permission from [23].

Time (hours)	Skin		Muscle		Articular tissue
	LIT	IM	LIT	IM	LIT	IM
0	nd	nd	nd	nd	nd	nd
0.5	124.9	4.8	1.5	33.3	25.8	18.6
1	42.3	t	3	t	19.3	0.3
2	15.6	t	23.8	t	10.8	t
4	10.9	t	19.3	t	8.3	t
7	t	nd	100.6	t	6.2	t
10	t	nd	102.2	t	7	t
24	nd	nd	14.9	nd	0.8	nd

nd = not detectable; t = trace.