Correlation between Chemical Composition of Curcuma domestica and Curcuma xanthorrhiza and Their Antioxidant Effect on Human Low-Density Lipoprotein Oxidation
Table 2
Percentage inhibition and IC50 value (μg/mL) of the methanol extracts and curcuminoids of Curcuma domestica and C. xanthorrhiza on human LDL peroxidation.
Sample
Concentration (g/mL)
Inhibition (%)
IC50 (g/mL)
6.25
84.14 ± 0.13
3.13
83.77 ± 0.13
Curcuma domestica
1.56
73.18 ± 0.78
0.31 ± 0.01
0.78
68.73 ± 0.79
0.39
50.45 ± 0.20
12.5
91.94 ± 0.92*
6.25
88.04 ± 0.52
Curcuma xanthorrhiza
3.13
77.82 ± 0.92
0.78 ± 0.03
1.56
62.23 ± 0.13
0.78
50.89 ± 1.05
1.56
98.81 ± 0.10*
0.78
93.57 ± 0.56
Demethoxycurcumin
0.39
84.23 ± 1.38
0.11 ± 0.01 (0.16 M)
0.20
64.42 ± 3.10
0.10
47.83 ± 3.25
1.56
93.20 ± 0.59*
0.78
88.71 ± 0.98
Bisdemethoxycurcumin
0.39
80.87 ± 1.67
0.05 ± 0.01 (0.33 M)
0.20
71.90 ± 2.45
0.10
56.01 ± 0.71
1.56
90.58 ± 0.82*
0.78
89.09 ± 0.95
Curcumin
0.39
78.25 ± 1.90
0.06 ± 0.01 (0.15 M)
0.20
58.15 ± 2.89
0.10
50.39 ± 3.43
5.00
76.3 ± 0.6
2.50
74.2 ± 0.2
Probucol
1.25
70.3 ± 0.1
0.30 ± 0.1 (0.57 M)
0.63
62.1 ± 1.6
0.31
48.9 ± 0.1
Probucol was used as a positive control. Values are presented as mean ± SEM (). * < 0.05 as compared with the control. IC50 values in M are in parentheses.
