NMDA Receptor-Dependent Synaptic Activity in Dorsal Motor Nucleus of Vagus Mediates the Enhancement of Gastric Motility by Stimulating ST36
Figure 2
Low frequency stimulation at ST36 increases NMDAR-mediated EPSCs in gastric-projecting neurons. (a) Representative gastric-projecting neuron which is labeled with retrograde tracer. Left: under fluorescent light; right: under bright-field illumination. The arrows point to the same neuron. Calibration bar: 20 μm. (b) Representative traces of labeled and unlabeled neurons in the brain slices from rats with and without low frequency stimulation at ST36. (c) NMDAR-mediated EPSCs are increased in labeled neurons from the stimulated rats. , compared to unlabeled neurons from the stimulated rats, unpaired test; , compared to the labeled neurons from control rats (without stimulation), , unpaired test. (d) The low frequency stimulation at ST36 does not change AMPA-receptor-(AMPAR-) mediated EPSCs in either labeled or unlabeled neurons, unpaired test.
