Effects of Fructus mume Extract on MAPK and NF-κB Signaling and the Resultant Improvement in the Cognitive Deficits Induced by Chronic Cerebral Hypoperfusion
Figure 7
F. mume prevented BCCAo-induced NF-B activation. (a) Representative western blot of cytosolic IκB-α (top) cytosolic NF-B p65 (middle), and nuclear NF-B p65 (bottom). (b, c) Cytosolic IB-α and cytosolic NF-κB p65 were significantly diminished in the BCCAo hippocampus (*). F. mume prevented the attenuation of cytosolic IκB-α and cytosolic NF-κB p65 (#) (d). Levels of nuclear NF-B p65 were increased in the BCCAo hippocampus (*). Levels of nuclear NF-B p65 were not increased in the BCCAo hippocampus treated with F. mume (#).
