Antidiabetic Effects of Add-On Gynostemma pentaphyllum Extract Therapy with Sulfonylureas in Type 2 Diabetic Patients

Table 1

Baseline clinical characteristics and laboratory findings of the patients.

	Baseline	After 4 weeks
𝑛	25	25
Age (years)	55.0 ± 9.0	55.0 ± 9.0
Sex (Male : Female)	15 : 10	15 : 10
Body weight (kg)	55.0 ± 9.6	55.1 ± 9.3
BMI (kg/m^2)	22.1 ± 3.6	22.2 ± 3.5
Waist (cm)	86.6 ± 8.9	86.6 ± 9.1
Hip (cm)	96.9 ± 6.6	96.4 ± 6.8
Systolic blood pressure (mmHg)	120.8 ± 7.6	120.4 ± 9.5
Diastolic blood pressure (mmHg)	78.6 ± 4.9	77.8 ± 5.4
Fasting plasma glucose (FPG) (mmol/L)	11.4 ± 1.3	9.3 ± 1.3*
Fasting plasma insulin (pmol/L)	99.0 ± 33.0	126.0 ± 55.8**
30-minute plasma insulin (pmol/L)	190.8 ± 113.4	267.6 ± 136.8**
120-minute plasma insulin (pmol/L)	303.0 ± 244.2	457.2 ± 233.4**
HbA1C (%)	9.9 ± 1.0	8.9 ± 0.7*
C-peptide (ng/mL)	0.8 ± 0.6	1.6 ± 0.8*
30-minute C-peptide (ng/mL)	1.4 ± 1.2	2.6 ± 1.3*
Cholesterol (mmol/L)	5.1 ± 1.2	4.5 ± 0.9**
Triglyceride (mmol/L)	3.0 ± 2.2	2.2 ± 1.3**
HDL-cholesterol (mmol/L)	1.2 ± 0.2	1.2 ± 0.3
LDL-cholesterol (mmol/L)	2.9 ± 0.8	2.5 ± 0.8**

Results are means ± SD, *𝑃<0.001, **𝑃<0.01.